Review Article

Effects of Light Intensity Activity on CVD Risk Factors: A Systematic Review of Intervention Studies

Table 1

Summary of included studies, sorted by disease status and duration of intervention.

Study referenceDisease statusDuration of interventionWeight status (based on mean BMI)Study designSample size = LIPA group (total)Age range (mean ± SD)Baseline activity levelModality of interventionDowns and Black ScoreStudy quality

[56]No9 moNo dataRCT33 (72)60–81 (63.9 ± 3.9)No dataLaboratory-based17Fair
[26]No24 wkOverweightRCT12 (36)18–45SedentaryFree-living16Fair
[30]No16 wkObeseRCT6 (25)(52.8 ± 7.2)SedentaryFree-living19Fair
[28]No16 wkOverweightRCT17 (51)20–50SedentaryLaboratory-based19Fair
[27]No16 wkOverweightRCT17 (51)20–50SedentaryLaboratory-based19Fair
[29]No16 wkOverweightRCT17 (51)20–50SedentaryLaboratory-based19Fair
[53]No12 wkNo dataNRCT10 (26)(25 ± 2.5)No exercise habitLaboratory-based15Low
[32]No10 wkOverweightRCD39≥55SedentaryLaboratory-based21Fair
[55]No7 wkNo dataRCT9 (24)18–30UntrainedLaboratory-based17 Fair
[35]No5 dOverweightRCD2335–65 (48.2 ± 7.9)SedentaryLaboratory-based21Fair
[57]No4 dNormalRCD18(21 ± 2)Physically inactiveLaboratory-based18Fair
[63]No~238 minNo dataRCD13(23.8 ± 0.9)Physically activeLaboratory-based19Fair
[54]No~214.5 minNormalRCD9(24.0 ± 4.0)Recreationally activeLaboratory-based17Fair
[49]No120 minNo dataRCD12(25.8 ± 1.2)Regular physical activityLaboratory-based14Low
[50]No120 minNormalCase series2218–23Regular structured runningLaboratory-based13Low
[44]No120 minNo dataRCD6(25 ± 2)Moderately trainedLaboratory-based15Low
[47]No90 minNormalRCD12(29.5 ± 6.2 male; 24.3 ± 1.4 female)Recreationally activeLaboratory-based15Low
[46]No90 minNo dataRCD12(28.2 ± 1.5)Recreationally activeLaboratory-based15Low
[51]No45 minNormalURCT22(23.22 ± 2.88)Runners (<5 miles/wk)Laboratory-based15Low
[37]No40 minOverweightRCD12(46.2 ± 1.1)SedentaryLaboratory-based20Fair
[45]No35 minNormalRCD14(25.4 ± 1.8)Endurance trainedLaboratory-based16Fair
[40]No28 minOverweightRCD10(24 ± 3)No dataLaboratory-based18Fair
[38]No28 minObeseRCD1945–65Physically inactiveLaboratory-based24High
[39]No28 minObeseRCD1945–65Physically inactiveLaboratory-based22High
[52]No15 minNormalRCD622–39 (32 ± 4)AthletesLaboratory-based15Low
[48]No5 minNo dataRCD6(23.5 ± 0.9)SedentaryLaboratory-based14Low
[31]HPN12 wkObeseRCT20 (40)45–65SedentaryFree-living20Fair
[41]DM212 wkNo dataRCT29 (59)(60 ± 10)No dataLaboratory-based14Low
[42]CHF8 wkNo dataRCT7 (21)(58 ± 3)Habitually activeLaboratory-based16Fair
[33]GDM6 wkObeseCase control 10 (30)(33.4 ± 3.3)No dataFree-living16Fair
[34]Colon Cancer2 wkOverweightRCT10 (23)59–67No dataLaboratory-based14Low
[36]MS≈103 minObeseRCD14(43 ± 9)Physically inactiveLaboratory-based16Fair
[43]HIV infected60 minNo dataRCT11 (38)(42.9 ± 7.5)Exercise-naiveLaboratory-based18Fair

BMI: body mass index; DM2: diabetes mellitus type 2; GDM: gestational diabetes mellitus; HIV: human immunodeficiency virus; HPN: hypertension; LIPA: light intensity physical activity; min: minute; mo: month; MS: metabolic syndrome; NRCT: nonrandomized controlled trial; RCD: randomized cross-over design; RCT: randomized controlled trial; URCT: uncontrolled randomized clinical trial; wk: week. Physical inactivity is defined as not meeting at least 150 minutes of moderate intensity physical activity or 75 minutes of vigorous intensity physical activity. Compared to a control group with no prescribed activity. Compared to a sitting group. Disease status and baseline activity level (using the terminology of the primary study) presented were as per inclusion criteria.