Prevalence and Risk Factors of Prostate Cancer in Chinese Men with PSA 4–10 ng/mL Who Underwent TRUS-Guided Prostate Biopsy: The Utilization of PAMD Score

Table 2

Multivariable analysis of risk factors for presence of PCa and HGPCa.

	Prostate cancer				High grade prostate cancer
	Coefficient	OR	95% CI	value	Coefficient	OR	95% CI	value
%fPSA^∧	−0.357	0.700	0.391–1.252	0.229	−0.491	0.612	0.331–1.133	0.118
PV^∧	1.555	4.736	2.687–8.348	<	1.407	4.082	2.237–7.451	<
Age^∧	1.513	4.539	2.591–7.952	<	1.017	2.765	1.546–4.948
MRI	1.607	4.990	2.687–9.266	<	2.103	8.187	3.970–16.884	<
DRE	0.861	2.366	1.162–4.815		1.108	3.027	1.479–6.194

Statistically significant.
^∧Calculated as dichotomous variable (%fPSA ≤0.16 versus >0.16; PV ≦50 mL versus >50 mL; age ≤68 versus >68).
PCa = prostate cancer; HGPCa = high grade prostate cancer; %fPSA = percentage of free PSA; PV = prostate volume; MRI = magnetic resonance imaging; DRE = digital rectal examination; OR = Odds Ratio; CI = confidence interval.