Mammalian Cell Culture Process for Monoclonal Antibody Production: Nonlinear Modelling and Parameter Estimation

Table 7

Monte Carlo parameter means and standard deviation over complete measurement set.

Kinetic parameters	Mean value	Standard deviation
[pmol/(cell h)]	8.127 10^−4	44
[pmol/(cell h)]	2.868 10^6	51
[pmol/(cell h)]	2.441 10^5	63
[pmol/(cell h)]	1.330 10^2	71
[pmol/(cell h)]	7.873	23
[pmol/(cell h)]	3.923 10^5	35
[pmol/(cell h)]	3.157 10^3	93
[pmol/(cell h)]	4.067 10^−6	24
[pmol/(cell h)]	2.991 10^4	36
[mM]	8.936 10^5	17
[mM]	7.030 10^4	29
[mM]	3.684 10^4	5
[mM]	7.31 10^2	29
[mM]	2.565 10^3	14
[mM]	0.026	13
[mM]	2.295 10^4	87
[mM]	9.273 10^3	51
[mM]	0.649	116
[mM]	6.224 10^5	39
[mM]	1.814 10^3	44
[mM]	4.657 10^4	75
	0.048	2
	0.070	0.73