Research Article

Tetramethylpyrazine Inhibits Activation of Hepatic Stellate Cells through Hedgehog Signaling Pathways In Vitro

Figure 1

TMP inhibits both the activation of HSCs. Effects of TMP on the activities of Smo, Patched and Hhipin HSC-T6 cells. The levels of Smo, Patched, and Hhip protein levels were determined by western blot analysis and normalized by β-actin. Significance is defined as follows: , , and compared with control. The DMSO was defined as control.