Research Article
Mushroom β-Glucan May Immunomodulate the Tumor-Associated Macrophages in the Lewis Lung Carcinoma
Table 2
Figure out the parameter detected in the presented study.
| | Normal mice | Tumor-bearing mice | | PC (distilled water) | PB (fed with Ganoderma beta-glucan) | TC (fed with distilled water) | TM (fed with celecoxib) | TB (fed with Ganoderma beta-glucan) | TX (fed with Ganoderma beta-glucan) |
| TGF-β (serum) | — | — | — |
↓ | ↓ | ↓ |
| IL-12 (lung) | — | — | — | — | — | — |
| IL-12 (tumor) | ✗ | ✗ | — | — |
↑ | ↑ |
| GM-CSF (lung) | — | — | — | — | — | — |
| GM-CSF (tumor) | ✗ | ✗ | — | — | — | — |
| IFN-γ (lung) | — | ↑ | — | — | — | — |
| IFN-γ (tumor) | ✗ | ✗ | — | ↑ | ↑ | ↑ |
| IL-10 (lung) | — | — | — | — | — | — |
| IL-10 (tumor) | ✗ | ✗ | — | ↓ | ↓ | ↓ |
| M-CSF (lung) | — | — | — | — | ↓ | ↓ |
| M-CSF (tumor) | ✗ | ✗ | — | ↓ | — | — |
| TGF-β (lung) | — | — | — | — | — | — |
| TGF-β (tumor) | ✗ | ✗ | — | ↓ | ↓ | ↓ |
| IL-6 (lung) | — | — | — | — | — | — |
| IL-6 (tumor) | ✗ | ✗ | — | ↓ | ↓ | ↓ |
| COX-2 (lung) | — | ↓ | — | — | — | — |
| COX-2 (tumor) | ✗ | ✗ | — | ↓ | ↓ | ↓ |
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