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BioMed Research International
Volume 2015 (2015), Article ID 608054, 3 pages
http://dx.doi.org/10.1155/2015/608054
Editorial

Genetic and Epigenetic Effects of Environmental Mutagens and Carcinogens

1Department of Health Sciences, University of Genoa, Via Antonio Pastore 1, 16132 Genoa, Italy
2Toxicology Institute, Preventive Medical College, Third Military Medical University, Chongqing 400038, China
3Department of Genetics and Evolutionary Biology, Institute of Bioscience, University of São Paulo, 05508-090 São Paulo, SP, Brazil
4Laboratory of Toxicology UT-BIORAD, ENEA, CR Casaccia, Via Anguillarese 301, 00123 Rome, Italy

Received 21 June 2015; Accepted 22 June 2015

Copyright © 2015 Alessandra Pulliero et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. N. Wogan, “Molecular epidemiology in cancer risk assessment and prevention: recent progress and avenues for future research,” Environmental Health Perspectives, vol. 98, pp. 167–178, 1992. View at Publisher · View at Google Scholar · View at Scopus
  2. R. L. Jirtle and M. K. Skinner, “Environmental epigenomics and disease susceptibility,” Nature Reviews Genetics, vol. 8, no. 4, pp. 253–262, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. A. P. Wolffe and M. A. Matzke, “Epigenetics: regulation through repression,” Science, vol. 286, no. 5439, pp. 481–486, 1999. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Izzotti, “Molecular medicine and the development of cancer chemopreventive agents,” Annals of the New York Academy of Sciences, vol. 1259, no. 1, pp. 26–32, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Izzotti and A. Pulliero, “The effects of environmental chemical carcinogens on the microRNA machinery,” International Journal of Hygiene and Environmental Health, vol. 217, no. 6, pp. 601–627, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. F. Doolittle, T. D. P. Brunet, S. Linquist, and T. R. Gregory, “Distinguishing between ‘Function’ and ‘Effect’ in genome biology,” Genome Biology and Evolution, vol. 6, no. 5, pp. 1234–1237, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. J. E. Klaunig, L. M. Kamendulis, and Y. Xu, “Epigenetic mechanisms of chemical carcinogenesis,” Human and Experimental Toxicology, vol. 19, no. 10, pp. 543–555, 2000. View at Publisher · View at Google Scholar · View at Scopus
  8. D. Huang, Y. Zhang, Y. Qi, C. Chen, and W. Ji, “Global DNA hypomethylation, rather than reactive oxygen species (ROS), a potential facilitator of cadmium-stimulated K562 cell proliferation,” Toxicology Letters, vol. 179, no. 1, pp. 43–47, 2008. View at Publisher · View at Google Scholar · View at Scopus