BioMed Research International / 2015 / Article / Tab 4

Research Article

Modern Evaluation of Liquisolid Systems with Varying Amounts of Liquid Phase Prepared Using Two Different Methods

Table 4

Properties of liquisolid tablets prepared by simple blending and spraying.

SampleSimple blendingSpraying
FriabilityDisintegrationUniformity
of mass
Drug
content
HeightFriabilityDisintegrationUniformity
of mass
Drug
content
Height
%smg%mm%smg%mm

40%w0.523.0 ± 0.0650.23 ± 5.28103.01 ± 5.088.20 ± 0.070.9518.0 ± 0.0650.12 ± 3.3795.58 ± 5.006.06 ± 0.05
50%w0.1038.0 ± 3.0649.76 ± 4.2598.82 ± 7.956.48 ± 0.150.1824.0 ± 5.0657.07 ± 6.7096.55 ± 1.706.22 ± 0.13
60%w0.0650.0 ± 3.0654.43 ± 5.9899.86 ± 6.665.59 ± 0.090.0460.0 ± 13.0650.50 ± 1.97106.07 ± 0.774.96 ± 0.11
70%w0.23159.0 ± 3.0651.31 ± 4.1392.29 ± 3.114.90 ± 0.040.0498.0 ± 17.0656.66 ± 6.3397.35 ± 0.804.66 ± 0.06
80%w0.43107.0 ± 5.0655.13 ± 7.71109.42 ± 4.674.73 ± 0.080.0535.0 ± 0.0656.82 ± 4.30103.43 ± 4.295.05 ± 0.02
90%w0.5651.0 ± 0.0664.31 ± 5.4666.10 ± 3.834.88 ± 0.030.0373.0 ± 0.0654.74 ± 5.6095.92 ± 1.894.81 ± 0.02
100%w0.7939.0 ± 0.0649.44 ± 3.68116.76 ± 5.034.87 ± 0.030.0830.0 ± 0.0655.75 ± 0.8290.55 ± 1.954.47 ± 0.17
110%w0.8540.0 ± 4.0659.11 ± 3.29118.19 ± 13.154.94 ± 0.050.2525.0 ± 0.0652.93 ± 1.70109.20 ± 1.144.61 ± 0.05
120%w1.4521.0 ± 0.0653.12 ± 1.7885.68 ± 23.704.82 ± 0.050.1618.0 ± 0.0658.05 ± 1.05112.38 ± 0.924.30 ± 0.00

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.