Clinical Study
Initial Experience of Sorafenib Neoadjuvant Therapy Combined with Retroperitoneoscopy in Treating T2 Large Renal Carcinoma
Table 1
Patients’ information and perioperative parameters of the sorafenib treatment group.
| Patient | Gender | Age (yr) | TNM staging | Drug administration time (d) | Drug discontinuation time (d) | Drug side effects | Toxicity grading | LD before medication (cm) | LD after medication (cm) | MD before medication (HU) | MD after medication (HU) | Operation time (min) | Intraoperative blood loss (mL) | Perioperative complications | Fuhrman grading | Length of stay (d) |
| 1 | F | 52 | T2aN0M0 | 41 | 13 | None | 0 | 8.8 | 7.1 | 73 | 59 | 190 | 650 | None | I | 8 | 2 | M | 65 | T2bN1M1 | 36 | 8 | Hypertension | I | 12.1 | 11.9 | 69 | 61 | 225 | 1980 | Intraoperative hemorrhea and peritoneal damage | II | 14 | 3 | M | 71 | T2aN0M1 | 48 | 14 | Hand-foot syndrome | I | 9.1 | 8.2 | 82 | 77 | 210 | 530 | None | II | 11 | 4 | F | 69 | T2aN1M1 | 51 | 16 | Hypertension | I | 10.5 | 9.6 | 59 | 56 | 102 | 810 | None | II | 13 | 5 | F | 73 | T2aN0M0 | 81 | 7 | Diarrhea | II | 7.2 | 6.8 | 71 | 65 | 120 | 480 | None | II | 12 |
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LD: longest dimension of the tumor; MD: medium density of the tumor.
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