Screening and Identification of ssDNA Aptamer for Human GP73

Figure 2

The SELEX screening of aptamers for GP73 and sequence analysis and structure prediction of aptamer A10-2. (a) The SELEX procession was monitored by ELASA. The binding capacity between selected ssDNA pool and GP73 was gradually increased with the increase of SELEX screening procession. (b) The encoding sequences of thirty aptamers derived from the tenth round of ssDNA pool were aligned and the sequences of two aptamers were the same, which were named A10-2. (c) The secondary structure and dG of A10-2 were analyzed using online mFold software. Asterisks indicate statistical significance: ^*< and ^**>.

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