Research Article

Organotypic Culture of Breast Tumor Explants as a Multicellular System for the Screening of Natural Compounds with Antineoplastic Potential

Figure 1

Viability of cultures breast cancer explants. To determine the optimal time for performing the experiments with bioactive compounds, explants were cultivated in DMEM/F12 supplemented medium for 24, 48, 72, and 96 h. The viability was assessed by the Alamar Blue assay. Values reflect means ± SD. Asterisks () indicate significant statistical differences ().