Long Noncoding RNA Expression Signatures of Metastatic Nasopharyngeal Carcinoma and Their Prognostic Value

Figure 5

Expression levels of enhancer lncRNAs and their nearby coding genes based on genome relationship analysis. A total of 245 enhancer lncRNAs upstream of their nearby coding genes were differentially expressed; 58 of these enhancer lncRNAs were upregulated and 187 were downregulated. Additionally, 217 enhancer lncRNAs downstream of their nearby coding genes were differentially expressed; 45 of these enhancer lncRNAs were upregulated and 172 were downregulated. Some of the nearby coding genes displayed consistent upregulation or downregulation in concert with that of their corresponding enhancer lncRNAs, whereas other nearby coding genes displayed opposite differences.