Research Article
Investigation of the Vitamin D Receptor Polymorphisms in Acromegaly Patients
Table 2
Distribution of vitamin D receptor (VDR) genotypes and alleles in acromegaly patients and control subjects.
| | | Patients (, %) | Controls (, %) |
| | TaqI genotypes/alleles | | | | TT | 19 (36.5) | 38 (45.8) | | Tt | 29 (55.8) | 38 (45.8) | | tt | 4 (7.7) | 7 (8.4) | | T | 67 (64.4) | 114 (68.7) | | t | 37 (35.6) | 52 (31.3) | | ApaI genotypes/alleles | | | | AA | 20 (38.5) | 28 (33.7) | | Aa | 25 (48.1) | 43 (51.8) | | aa | 7 (13.5) | 12 (14.5) | | A | 65 (62.5) | 99 (59.6) | | a | 39 (37.5) | 67 (40.4) | | FokI genotypesa/alleles | | | | FF | 15 (28.8) | 29 (34.9) | | Ffb | 32 (61.5) | 34 (41) | | ffc | 5 (9.6) | 20 (24.1) | | F | 62 (59.6) | 92 (55.4) | | f | 42 (40.4) | 74 (44.6) |
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Frequencies of FokI genotypes between patients and controls ().
bFf versus FF + ff (OR: 1.5, 95% CI: 1.07–2.1; ).
cff versus FF + Ff (OR: 0.4, 95% CI: 0.16–0.99; ).
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