Figure 10: ((a)–(c)) 24-week MSQL scores in long-term follow-up subjects. (a) Subject 01 has essentially plateaued after week 8 throughout to end of the second study. Subject 02 shows scores increasing over time demonstrating minimally important differences based on Cole et al. criteria by week 24. (b) Subject scores seem to peak by week 8 with both subjects showing similar scores reported at week 24. (c) Subject 2 scores remain consistent throughout the study while subject 01 shows steady improvement from baseline to the end of week 24. MSQL: Migraine-Specific Quality of Life Measure.