Table 5: Summary comparison of measured outcomes ().

ID1ICCI3MIDAS8HIT-62MSQL4Headache diary
R7E5P6Days/monthIntensity

1
2
3
4
5
6
7
8
9
10
11

: remained essentially the same; : decreased; : increased; —: no clinically significant change observed. A blank field in the chart indicates a clinically significant change was observed.
Five subjects demonstrated an increase in ICCI similar to case study results.
Three-subject compliance index remained essentially the same while two showed a decrease. Two subjects showed ICCI increase and a positive change in all HRQoL measures.
ID: subject identification.
2HIT-6: Headache Impact Test-6.
3ICCI: intracranial compliance index.
4MSQL: Migraine-Specific Quality of Life Measure.
5MSQL-E: Migraine-Specific Quality of Life Measure-Emotional.
6MSQL-P: Migraine-Specific Quality of Life Measure-Physical.
7MSQL-R: Migraine-Specific Quality of Life Measure-Restrictive.
8MIDAS: Migraine Disability Assessment Scale.