Vascular Damage in Resistant Hypertension: TNF-Alpha Inhibition Effects on Endothelial Cells

Figure 4

Gene expression of serum-treated HUVECs. Expression of genes normalized for GAPDH was investigated in human umbilical vein endothelial cells stimulated with plasma obtained from normotensive subjects (NT, ) or resistant hypertensive patients (RHTN, ) and treated with vehicle or infliximab. (a) Gene expression of endothelial nitric oxide synthase (ENOS). (b) Gene expression of catalase (CAT). (c) Gene expression of inducible nitric oxide synthase (INOS). (d) Gene expression of arginase II (ARGII) (mean ± SD, versus NT vehicle). The experiments were performed in duplicate.

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