Comparative Study on the Cytoprotective Effects of Activated Protein C Treatment in Nonsteatotic and Steatotic Livers under Ischemia-Reperfusion Injury

Figure 5

Phosphorylation of AMPK in steatotic liver tissue. In ND mice, there was no significant difference in phosphorylation of AMPK regardless of the APC administration at 4 or 24 h (a, b). APC significantly increased phosphorylation of AMPK at 4 h in HF mice () (c). At 24 h, however, there was no significant difference in phosphorylation of AMPK between HF-APC and HF-Control mice (d).

(a)

(b)

(c)

(d)