Potential Therapeutic Benefit of Combining Gefitinib and Tamoxifen for Treating Advanced Lung Adenocarcinoma

Table 1

Clinical characteristics of study population.

Characteristic	Number of patients	%
Age
>60	35	63%
≦60	20	37%
Sex
Male	25	45%
Female	30	55%
Smoking history
Current smoker	6	11%
Ever smoker habit	17	31%
Never	32	58%
Stage
IIIa	2	4%
IIIb	9	16%
IV	44	80%
Tumor differentiation
Moderate	36	65%
Poor	19	35%
TTF1
Positive	45	82%
Negative	10	18%
EGFR
Exon 19 deletion	10	18%
L858 mutation	14	26%
Unfound	31	56%
ER- nuclear expression
Strong (≧6)	38	69%
Weak	17	31%
ER- cytosolic expression
Strong (≧6)	27	49%
Weak	28	51%
ER- nuclear expression
Strong (≧6)	39	71%
Weak	16	29%
ER- cytosolic expression
Strong (≧6)	21	38%
Weak	34	62%
Total	55