Mechanistic Studies on the Use of Polygonum multiflorum for the Treatment of Hair Graying

Figure 5

Hair color (a), total melanin contents (b), and microscopic images (c) of mice hair at the end of the research. (a) Mice appearances in control (left) and model (right) group. Obvious decolorization was observed in mice hair after H₂O₂ treatment. (b) Average total melanin content in a group was measured with a UV-Vis spectrophotometer. (c) Photomicrographs of mice hair in all groups demonstrate their color alteration. Mice were in control (A) or untreated (B), TSG (0.034 g/kg and 0.068 g/kg, oral and topical) (C), PMR (0.576 g/kg and 1.152 g/kg, oral and topical) (D), and PMRP (0.576 g/kg and 1.152 g/kg, oral and topical) (E) groups.

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