Mechanistic Studies on the Use of Polygonum multiflorum for the Treatment of Hair Graying

Figure 6

α-MSH (a), MC1R (b), TYR (c), TRP-1 (d), and TRP-2 (e) concentrations in skins of different groups. (X ± SD, ). Mice were in control (A) or untreated (B), TSG (0.034 g/kg and 0.068 g/kg, oral and topical) (C), PMR (0.576 g/kg and 1.152 g/kg, oral and topical) (D), and PMRP (0.576 g/kg and 1.152 g/kg, oral and topical) (E) groups. The α-MSH, MC1R, TYR, TRP-1, and TRP-2 contents in the skin tissue were measured by Elisa kits. The # indicates a significant difference compared with untreated hair graying group. ; ; . The indicates a significant difference compared with control group. ; ; .

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