The Type III Secretion System (T3SS) of Chlamydophila psittaci Is Involved in the Host Inflammatory Response by Activating the JNK/ERK Signaling Pathway

Figure 3

MAPK pathway assay of THP-1 cells infected with C. psittaci pretreated with iron sulfate and INP0007. The cells in each group were collected at 44 h p.i. The expression levels of p38, ERK, and JNK were analyzed by Western blot analysis. The expression levels of phospho-p38, phospho-ERK, and phospho-JNK were increased in the cells infected with C. psittaci. Iron sulfate and INP0007 pretreatment inhibited the increased expression. Cps, THP-1 cells infected with C. psittaci.