Novel Mechanisms of Spinal Cord Plasticity in a Mouse Model of Motoneuron Disease

Figure 6

Significant correlations between the actual values of functional performance (a) or protein expression levels ((b)–(e)) with those predicted by the multivariate regression models after the application of backward stepwise regression. The final regression models represented in the graphs are reported in the grey window.

(a) Predicted MD = 0.549 − 0.361 [Shh] − 0.128 [Noggin]

(b) Predicted Shh = 0.591 + 0.467 [TDP-43]

(c) Predicted TDP-43 = 1.174 [Shh] + 0.178 [Noggin] − 0.439 [Numb] − 0.099

(d) Predicted Noggin = 1.352 [TDP-43] + 1.430 [Numb] − 1.410

(e) Predicted Numb = 0.350 + 1.254 [Shh] + 0.322 [Noggin] − 1.197 [TDP-43]