BioMed Research International / 2015 / Article / Tab 2

Research Article

Is Lipoprotein-Associated Phospholipase A2 a Link between Inflammation and Subclinical Atherosclerosis in Rheumatoid Arthritis?

Table 2

Results of simple regression models among the 71 patients with early RA with the concentration of Lp-PLA2 at T0 as the dependent variable.

Lp-PLA2 at T0
β95% CI value

IMT T0 (n = 70)9.7/mm2.1; 17.20.013
IMT T5 (n = 70)8.8/mm1.4; 16.20.02
FMD T0 (n = 70)−2.4/%−4.5; −0.40.02
FMD T5 (n = 70)−2.5/%−4.6; −0.50.02
Non-HDL-cholesterol T0 (n = 54)16.9/mmolL−15.8; 28.00.004
HDL T0 (n = 55)−22.6/mmolL−1−42.0; −3.10.02
Diastolic blood pressure T0 (n = 66)1.3/mmHg0.1; 2.50.04
Ever smoking (n = 70)0.8/year0.08; 1.40.03
SCORE T0 (n = 53)11.4/unit3.3; 19.50.007
Reynolds Risk Score T0 (n = 38)5.2/unit1.5; 8.80.007
Larsen score T0 (n = 50)2.9/unit0.013; 5.900.05

Still significant after adjustment for sex and age.
RA: rheumatoid arthritis; Lp-PLA2: lipoprotein-associated phospholipase A2; IMT: intima media thickness; FMD: flow mediated dilation; HDL: high-density lipoproteins.