Activation of Sonic Hedgehog Leads to Survival Enhancement of Astrocytes via the GRP78-Dependent Pathway in Mice Infected with <i>Angiostrongylus cantonensis</i>

<div>Expression of Shh and GFAP in activated astrocytes by culturing with<i> Angiostrongylus cantonensis</i> soluble antigens. Astrocytes were treated with the 500 <i>μ</i>g antigens for 2 h. Increases in the levels of Shh and GFAP expressions were detected by immunofluorescence staining of normal and antigen treated astrocytes. Magnification is 1000x (GFAP: green; Shh: red; colocalization of GFAP and Shh: yellow).</div>

BioMed Research International

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Figure 5

Figure 5: Activation of Sonic Hedgehog Leads to Survival Enhancement of Astrocytes via the GRP78-Dependent Pathway in Mice Infected with <i>Angiostrongylus cantonensis</i> 

Figure 5 | Activation of Sonic Hedgehog Leads to Survival Enhancement of Astrocytes via the GRP78-Dependent Pathway in Mice Infected with Angiostrongylus cantonensis 