The Association between Serum LDL Cholesterol and Genetic Variation in Chromosomal Locus 1p13.3 among Coronary Artery Disease Patients

Table 2

Frequency of genotypes and alleles among study subjects based upon the significance of coronary artery stenosis stratification in CAD patients.

SNPs	Genotype	(%)	Group A; Insignificant stenosis	Group B; Significant stenosis
rs599839 A>G	AA	107 (48.4)	48 (56.5)	59 (43.4)	3.668	0.159
	AG	36 (16.3)	11 (12.9)	25 (18.4)
	GG	78 (35.3)	26 (30.6)	52 (38.2)
MAF	G (0.434)		G (0.371)	G (0.474)	3.682	0.032
rs646776 T>C	TT	170 (76.9)	73 (80.2)	97 (72.9)	1.568	0.456
	TC	18 (8.0)	6 (6.6)	12 (9.0)
	CC	36 (16.1)	12 (13.2)	24 (18.1)
MAF	C (0.201)		C (0.165)	C (0.236)	2.119	0.146
rs4970834 C>T	CC	122 (54.2)	48 (53.9)	74 (54.4)	4.147	0.125
	CT	40 (17.8)	11 (12.4)	29 (21.3)
	TT	63 (28)	30 (33.7)	33 (24.3)
MAF	T (0.369)		T (0.425)	T (0.316)	0.934	0.317

Data are presented by frequency for minor allele [MAF] and value is significant at >0.05. Frequency of alleles is presented as a percentage. Data were analyzed by chi-square test (2 degrees of freedom) with Bonferroni adjustments. Two-tailed value is significant at <0.05.