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BioMed Research International
Volume 2015 (2015), Article ID 687635, 20 pages
http://dx.doi.org/10.1155/2015/687635
Research Article

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β-Globin Gene with the IVSI-6 Thalassemia Mutation

1Department of Life Sciences and Biotechnology, Biochemistry and Molecular Biology Section, Ferrara University, 44121 Ferrara, Italy
2Laboratory for the Development of Pharmacological and Pharmacogenomic Therapy of Thalassemia, Biotechnology Center, Ferrara University, 44121 Ferrara, Italy
3Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, Turin University, 10126 Turin, Italy
4Laboratory for Chemical and Clinical Analysis and Microbiology, University Hospital, Cona, 44124 Ferrara, Italy
5Department of Biomedical and Specialty Surgical Sciences, Medical Genetic Unit, Ferrara University, 44121 Ferrara, Italy
6Division of Hematology-Oncology, Department of Pediatrics, Weill Cornell Medical College, New York, NY 10065, USA

Received 8 September 2014; Revised 3 December 2014; Accepted 3 December 2014

Academic Editor: Oreste Gualillo

Copyright © 2015 Giulia Breveglieri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Giulia Breveglieri, Irene Mancini, Nicoletta Bianchi, et al., “Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β-Globin Gene with the IVSI-6 Thalassemia Mutation,” BioMed Research International, vol. 2015, Article ID 687635, 20 pages, 2015. doi:10.1155/2015/687635