Shaped Singular Spectrum Analysis for Quantifying Gene Expression, with Application to the Early Drosophila Embryo

Figure 1

An example of overcorrection in gene expression data causing the subtraction of the reference gene pattern (the seven-striped ftz and eve patterns; dark magenta) from the pattern under study (hb and Kr gene products (transcription factors); light blue). Visualization by PointCloudXplore tools [7], BDTNP embryos hb “v5-s11512-2oc06-25” ((a) and (c)), Kr “v5-s12169-24oc07-22” ((b) and (d)); (c) is the same as (a) with added ftz; (d) is the same as (b) with added eve.

(a)

(b)

(c)

(d)