Myeloperoxidase-Related Chlorination Activity Is Positively Associated with Circulating Ceruloplasmin in Chronic Heart Failure Patients: Relationship with Neurohormonal, Inflammatory, and Nutritional Parameters

Figure 1

Schematic diagram indicating the relationship between Myeloperoxidase-related chlorinating activity and Ceruloplasmin (Cp). Ceruloplasmin binding to MPO determines reduction of the active Compound I to Compound II and prevents the recycling of Compound II back to the active enzyme.