Review Article

Exercise and BMI in Overweight and Obese Children and Adolescents: A Systematic Review and Trial Sequential Meta-Analysis

Figure 6

Trial sequential analysis results. Trial sequential meta-analysis of exercise versus control for changes in BMI in kgmāˆ’2. The dashed inward sloping lines to the left represent trial sequential monitoring boundaries while the outward dashed sloping lines to the right represent futility boundaries. The solid black line represents the -curve and the black squares represent the cumulative results with each accumulating study from earliest (2004) to most recent (2014) year. The cumulative -curve, that is, black solid line with filled squares, crossed the monitoring boundaries in 2010, confirming that exercise reduces BMI in kgmāˆ’2 in overweight and obese children and adolescents and is unlikely to be reversed with additional studies in future years.