Research Article
Antimicrobial, Antioxidant, and Cytotoxic Properties of Vasicine Acetate Synthesized from Vasicine Isolated from Adhatoda vasica L.
Table 1
Antimicrobial activity of Vasicine acetate (500 µg/mL) using disc diffusion method (zone of inhibition in mm).
| Organism | Vasicine (µg/mL) | Vasicine acetate (µg/mL) | Streptomycin (10 µg/mL) |
| Gram positive | | | | M. luteus | — | 9 | 26 | E. aerogenes | — | 10 | 22 | S. aureus | 8 | 8 | 14 | S. epidermidis | 8 | 10 | 14 | B. subtilis | — | 9 | 22 | Gram negative | | | | S. flexneri | — | 8 | 30 | S. paratyphi-B | — | — | 18 | P. aeruginosa | — | 10 | 30 | S. typhimurium | — | — | 24 | Clinical isolates | | | | E. coli (ESBL-3984) | — | 8 | 12 | E. coli (ESBL-3904) | — | 11 | 12 | K. pneumoniae (ESBL-3971) | — | — | 16 | K. pneumoniae (ESBL-75799) | — | 10 | 16 | K. pneumoniae (ESBL-3894) | — | 8 | 14 | K. pneumoniae (ESBL-3967) | 8 | — | 16 | S. aureus (MRSA) | — | — | — |
| | | | Ketoconazole (25 µg/mL) |
| Fungi | | | | C. albicans | — | — | 28 | B. cinerea | — | — | 22 | T. rubrum | — | — | 22 | T. mentagrophytes | — | — | 24 | Scopulariopsis sp. | — | — | 26 | A. flavus | — | — | 28 | M. pachydermatis | — | — | 26 |
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(—) no activity; Streptomycin: standard antibacterial agent; Ketoconazole: standard antifungal agent.
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