Review Article

Molecular Biomarkers for Embryonic and Adult Neural Stem Cell and Neurogenesis

Figure 1

The schematic of embryogenesis and the specific markers expressed in specific time-line. (a) The process of embryogenesis. With the beginning of neuroepithelial cells, a series of cell types are produced, including radial glial cells, neurogenic intermediate progenitor cells, oligogenic intermediate progenitor cells, neurons, and astrocytes. (b) The specific markers indicate the specific cell types generated during the process of neurogenesis [16]. CP, cortical plate; DL, deep layer; GC, glial cells; IZ, intermediate zone; L1–6, layers 1–6; MZ, marginal zone; nIPC, neurogenic intermediate progenitor cell; NECs, neuroepithelium cells; oIPC, oligogenic intermediate progenitor cell; UL, upper layer; CPN, callosal projection neurons. RGCs, radial glial cells; SVZ, subventricular zone; SP, subplate; VZ, ventricular zone. CThPN, corticothalamic projection neurons; SCPN, subcerebral projection neurons.
(a)
(b)