Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts

Figure 3

Intersection barplot showing the number of DEG between several consecutive PDs in MRC-5 and HFF for two different cutoffs ((a) + (c): FDR < 0.05; (b) + (d): FDR < 0.01 and |log 2-fold-change| > 1). In each plot, identical colors across different bars indicate the same set of DEG (intersection) while new colors indicate a new set of DEG (from left to right). (a) and (b) indicate genes which were found in MRC-5 and likewise in HFF. (c) and (d) show the same number of DEG but HFF is listed first in order to show the number of genes which were found likewise in MRC-5. For instance in (a), the red colored parts of all bars encode DEG found in MRC-5 between PD32 and PD42 while yellow colored parts of bars denote “new” DEG found in HFF between PD16 and PD26.

(a)

(b)

(c)

(d)