Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts

Figure 4

Spearman correlation of RNA-seq and qRT-PCR expression profiles for selected DEG commonly regulated in MRC-5 and HFF. Almost all genes exhibit a positive correlation between both measurement techniques (exception: EGR1 in MRC-5). With age, the first four genes (EGR1-ID3) are downregulated (first PD compared to last PD), while the later are upregulated (CCND1-WNT16).