Table 2: Methylation level of four genes in the serum of age-matched controls, CAG patients, and GC patients.

GeneMethylation level (mean ± SD) value
ControlsCAGGCOverallControls versus CAGControls versus GCCAG versus GC

FLNC0.082 ± 0.0630.147 ± 0.1840.849 ± 1.1000.0050.3090.0020.019
THBS10.051 ± 0.0390.058 ± 0.0490.836 ± 1.118<0.0010.259<0.001<0.001
UCHL10.041 ± 0.0230.044 ± 0.0100.549 ± 0.614<0.0010.08<0.0010.016
DLEC10.189 ± 0.0650.203 ± 0.0730.989 ± 0.7670.0120.6620.0050.033

SD, standard deviation; GC, gastric cancer; CAG, chronic atrophic gastritis; value calculated by nonparametric Kruskal-Wallis test; value calculated by Bonferroni correction.