Table 4: Correlations between clinicopathological features and methylation status of genes in GC patients.

Variables GC patientsFLNCTHBS1UCHL1DLEC1
M (%)M (%)M (%)M (%)

Age (years)0.9530.0210.4290.396
 <6028 (34)18 (64)13 (46)14 (50)24 (86)
 ≥6054 (66)37 (69)39 (72)32 (60)42 (78)
H. pylori infection0.0090.1060.0650.747
 No38 (46)20 (53)22 (58)20 (53)30 (79)
 Yes44 (54)35 (80)30 (68)26 (59)36 (81)
Tumor size (cm)0.1850.7970.9740.040
 <334 (42)20 (59)21 (62)19 (56)28 (82)
 ≥348 (58)35 (73)31 (65)27 (56)38 (79)
Differentiation0.0160.2230.3050.766
 Good/moderate54 (66)35 (65)35 (65)31 (57)47 (87)
 Poor28 (34)20 (71)17 (61)15 (54)19 (68)
TNM Stage0.1310.2620.0260.361
 I, II48 (59)29 (60)28 (58)22 (46)37 (77)
 III, IV34 (41)26 (76)24 (71)24 (71)29 (85)
Lymph node metastasis0.2330.8540.0140.705
 N029 (35)17 (59)18 (62)11 (38)24 (83)
 N1–353 (65)38 (72)34 (64)35 (66)42 (79)

M, methylation, (%); value calculated by Fisher’s exact test; values < 0.05 are presented in bold.