Research Article

The Effect of Covalently Immobilized FGF-2 on Biphasic Calcium Phosphate Bone Substitute on Enhanced Biological Compatibility and Activity

Figure 1

Schematic diagram of the surface modification procedure of biphasic calcium phosphate (BCP): (I) APTES treatment; (II) Bi-functional cross-linker (SMP) connection; (III) FGF-2 covalent immobilization.