Research Article

Folated Synperonic-Cholesteryl Hemisuccinate Polymeric Micelles for the Targeted Delivery of Docetaxel in Melanoma

Table 2

Physicochemical properties of drug-free FA-targeted PF127-Chol micelles and nontargeted ones.

FormulationsParticle size Zeta potential PDI
(nm)(mV)

P3S2599.9 ± 13.66−8.260.59 ± 0.08
P12S25144.56 ± 8.11−4.1600.39 ± 0.043
P3F25139.15 ± 3.18−2.30.49 ± 0.017
P12F2591.73 ± 5.47−3.680.529 ± 0.04
P3S40113.4 ± 3.92−1.730.459 ± 0.07
P12S4086.25 ± 3.97−2.1570.53 ± 0.02
P3F40192.3 ± 2.82−4.140.49 ± 0.20
P12F40131.7 ± 4.97−3.010.42 ± 0.060
Nontargeted96.53 ± 4.6−0.9520.542 ± 0.01