Identification of Novel Breast Cancer Subtype-Specific Biomarkers by Integrating Genomics Analysis of DNA Copy Number Aberrations and miRNA-mRNA Dual Expression Profiling

Table 1

The detected high frequency CNA regions (more than 40% across samples).

Gains			Losses
Subtype	Chromosome	Frequency (%)	Subtype	Chromosome	Frequency (%)
Luminal-A	5p15.3-q11.1	46.20	Luminal-A	1p36.3-31.2	55.80
Luminal-A	16p13.3-13.1	61.50	Luminal-A	11p15.5-15.4	42.30
Basal-like	2p25.3-24.2	42.50	Luminal-A	17p13.3-11.2	59.60
Basal-like	6p25.3-21.2	52.50	Luminal-A	18p11.3-q12.1	40.40
Basal-like	9p24.3-22.1	47.50	Luminal-A	19p13.3-13.2	42.30
Basal-like	10p15.3-11.1	62.50	Luminal-A	22q11.1-13.1	50.00
Basal-like	12p13.3-13.1	47.50	Basal-like	1p36.3-35.3	55.00
Basal-like	21q11.1-21.3	60.00	Basal-like	3p26.3-25.2	42.50
			Basal-like	4p16.3-15.3	50.00
			Basal-like	7p22.3-21.3	45.00
			Basal-like	8p23.3-23.1	67.50
			Basal-like	11p15.5-15.2	57.50
			Basal-like	13q11-14.3	57.50
			Basal-like	14q11.2-q13.1	42.50
			Basal-like	16p13-11.2	45.00
			Basal-like	17p13.3-11.2	67.50
			Basal-like	19p13.3-13.1	65.00
			Basal-like	22q11.1-12.1	50.00