Data: Initial tensor , rotation matrices, number of Monte Carlo trials , SNR = , GES and .
Result: Response surface of
for    to    do
Obtain (a rotated version of );
for    to    do
   (i) Simulate the diffusion signal at the sampling points defined by the GES under evaluation using the
Stejskal and Tanner [18] equation ;
(ii) Add Rician distributed noise to the synthetic signal to obtain given SNR;
(iii) Compute the diffusion tensor and the corresponding ;
(iv) Record the mean signal deviation ();
Algorithm 1: Pseudoalgorithm to compute response surface of .