The Place of Extensive Surgery in Locoregional Recurrence and Limited Metastatic Disease of Breast Cancer: Preliminary Results

Table 1

Patients’ and tumours’ characteristics at initial breast surgery.

Age
(i) 50	6
(ii) 50	18
Premenopausal status	9
Menopausal status	15
Histological subtypes (26 tumours analysed, 2 bilateral breast cancers)		Grade; (i) Grade I: 2; (ii) Grade II: 18; (iii) Grade III: 6; Hormonal receptors; (i) ER (+): 25; (ii) PR (+): 22; (iii) ER (−) + PR (−): 1 (DCIS grade III)
(i) Infiltrating ductal carcinoma	19
(ii) Mixed lobular and ductal carcinoma	2
(iii) Infiltrating lobular carcinoma	4
(iv) Pure DCIS	1
Initial breast surgery
(i) Surgical procedures	26
(ii) Breast-conserving surgery	10
(iii) Mastectomy (2 bilateral)	16
Axillary dissection performed in 26 cases
(i) Negative nodes	17
(ii) Positive nodes	9
Quality of resection
(i) R0	25
(ii) R1 (1 mm DCIS)	1
Adjuvant therapy
(i) Radiotherapy
(a) Yes	18
(b) No	8
(ii) Chemotherapy
(a) Yes	7
(b) No	17
Endocrine therapy (24 patients)
(i) Tamoxifen	22
(ii) Tamoxifen + GnRH agonist	1
(iii) Aromatase inhibitors	1

R0: complete resection of any visible tumour with a pathologic demonstration of negative resection margins.
R1: complete resection of any visible tumour with a pathologic demonstration of positive margins.
ER: estrogen receptor.
PR: progesterone receptor.