Research Article
Computational Analysis of the Binding Specificities of PH Domains
Figure 4
Electrostatic and hydrophobic surface representations of PH domains. Top: molecular surfaces coloured by electrostatic potential, from red (−10 kT/e) to blue (+10 kT/e). Bottom: Hydropathic surface representations, hydrophobicity, and hydrophilicity are coloured from red to blue.
| (a) BtkPH-Ins(1,3,4,5)P4 |
| (b) Grp1PH-Ins(1,3,4,5)P4 |
| (c) PlcδPH-Ins(1,4,5)P4 |
| (d) SpecPH-Ins(1,4,5)P4 |
| (e) Dapp1PH-Ins(1,3,4,5)P4 |