Comparison of Fine Needle Aspiration and Fine Needle Nonaspiration Cytology of Thyroid Nodules: A Meta-Analysis

Table 5

Performance of the four diagnostic studies.

Study	FNAC/FNNAC
	Histopathological diagnosis	TP	FP	FN	TP	Performance in diagnosis		Diagnostic criteria for malignancy	Notes
						Sensitivity (%)	Specificity (%)
de Carvalho et al. 2009 [10]	53/52	14/13	10/8	1/0	28/31	93.3/100	73.7/79.5	Suspicious or positive	Excluded ND
McElvanna et al. 2009 [19]	41/48	8/8	11/18	1/1	21/21	88.9/88.9	65.6/53.8	Not specified	Excluded inadequate cytology specimens
Schoedel et al. 2008 [21]	14/16	4/4	0/0	2/4	8/10	66.7/50	100/100	Suspicious or positive	Excluded I and ND
Tauro et al. 2012 [15]	38/38	2/1	0/0	0/1	36/36	100/50	100/100	Not specified

TP: true positive, TN: true negative, FP: false positive, and FN: false negative. Sensitivity (%) = TP/(TP + FN) 100%; specificity (%) = TN/(TN + FP) 100%. ND: nondiagnostic and I: indeterminate, including follicular lesion and atypical cells present.