Ultrastructural Morphology of Sperm from Human Globozoospermia

Table 1

Knockout mouse models of globozoospermia.

Mouse model	Protein name	Round head	Acrosome	Coiled tail around the nucleus	Reference
Gopc	Golgi-associated PDZ and coiled-coil motif-containing protein	Yes	Absent	Yes	[3]
Agfg1 (Hrb)	ArfGAP with FG repeats 1	Yes	Absent	Yes	[15]
Zpbp	Zona pellucida binding protein	Yes	Absent	Yes	[17]
Spaca-1	Sperm acrosome associated 1	Yes	Absent	Yes	[18]
Dpy19l2	Dpy-19-like 2 (C. elegans)	Yes	Absent	?	[19]
AKR-bs X 129	?	No (elongated)	Absent	No	[23]
Gba2	Beta glucosidase 2	Yes	Present (deformed)	No	[24]
Pick-1	Protein interacting with C kinase 1	Yes	Present (deformed)	No	[25]
Csnk2a2	Casein kinase 2, alpha prime polypeptide	No (oval)	Present (deformed)	Yes	[26]