Research Article

Clinical and Etiological Characteristics of Atypical Hand-Foot-and-Mouth Disease in Children from Chongqing, China: A Retrospective Study

Table 1

Demographic and clinical presentations of patients with atypical HFMD.

VariablesAtypical HFMD ()
   (%)
95% CI

Demographics
Age (years)
 ≤135 (54.7)53.7%~55.7%
 1–325 (39.1)37.9%~40.3%
 >34 (6.2)5.5%~6.9%
Sex
 Male40 (62.5)61.6%~63.4%
 Female24 (37.5)36.3%~38.7%
Residence
 Urban40 (62.5)61.6%~63.4%
 Rural24 (37.5)36.3%~38.7%
Children care
 Home care51 (79.7)79.1%~80.3%
 Nursery care10 (15.6)14.6%~16.6%
 Schooling3 (4.7)4.1%~5.3%
Symptoms
Fever
 ≥37.5°C51 (79.7)79.1%~80.3%
 <37.5°C13 (20.3)19.2%~21.4%
Cough
 Yes20 (31.3)30.1%~32.5%
 No44 (68.7)67.9%~69.5%
Rhinorrhea
 Yes15 (23.4)22.3%~24.5%
 No49 (76.6)76.0%~77.2%
Salivation
 Yes41 (64.1)63.2%~65.0%
 No23 (35.9)34.7%~37.1%
Diarrhea
 Yes9 (14.1)13.1%~15.1%
 No55 (85.9)85.5%~86.3%
Poor oral intake
 Yes43 (67.2)66.4%~68.0%
 No21 (32.8)31.6%~34.0%
Vomiting
 Yes5 (7.8)7.0%~8.6%
 No59 (92.2)92.0%~92.4%
Headache
 Yes2 (3.1)25.8%~36.2%
 No62 (96.9)96.8%~97.0%
Febrile seizure
 Yes8 (12.5)11.6%~13.4%
 No56 (87.5)87.1%~87.9%
Startle response
 Yes10 (15.6)14.6%~16.6%
 No54 (84.4)84.0%~84.8%
Altered consciousness
 Yes1 (1.6)1.2%~2.0%
 No63 (98.4)98.3%~98.4%
Limb trembling
 Yes2 (3.1)2.6%~3.6%
 No62 (96.9)96.8%~97.0%
Unsteady gait
 Yes1 (1.6)1.2%~2.0%
 No63 (98.4)98.3%~98.4%

HFMD, hand-foot-and-mouth disease. Statistical analysis was performed with SPSS version 17.0 (SPSS Inc., Chicago, IL, USA). A value of was considered statistically significant.