Clinical and Etiological Characteristics of Atypical Hand-Foot-and-Mouth Disease in Children from Chongqing, China: A Retrospective Study
Table 1
Demographic and clinical presentations of patients with atypical HFMD.
Variables
Atypical HFMD () (%)
95% CI
Demographics
Age (years)
≤1
35 (54.7)
53.7%~55.7%
1–3
25 (39.1)
37.9%~40.3%
>3
4 (6.2)
5.5%~6.9%
Sex
Male
40 (62.5)
61.6%~63.4%
Female
24 (37.5)
36.3%~38.7%
Residence
Urban
40 (62.5)
61.6%~63.4%
Rural
24 (37.5)
36.3%~38.7%
Children care
Home care
51 (79.7)
79.1%~80.3%
Nursery care
10 (15.6)
14.6%~16.6%
Schooling
3 (4.7)
4.1%~5.3%
Symptoms
Fever
≥37.5°C
51 (79.7)
79.1%~80.3%
<37.5°C
13 (20.3)
19.2%~21.4%
Cough
Yes
20 (31.3)
30.1%~32.5%
No
44 (68.7)
67.9%~69.5%
Rhinorrhea
Yes
15 (23.4)
22.3%~24.5%
No
49 (76.6)
76.0%~77.2%
Salivation
Yes
41 (64.1)
63.2%~65.0%
No
23 (35.9)
34.7%~37.1%
Diarrhea
Yes
9 (14.1)
13.1%~15.1%
No
55 (85.9)
85.5%~86.3%
Poor oral intake
Yes
43 (67.2)
66.4%~68.0%
No
21 (32.8)
31.6%~34.0%
Vomiting
Yes
5 (7.8)
7.0%~8.6%
No
59 (92.2)
92.0%~92.4%
Headache
Yes
2 (3.1)
25.8%~36.2%
No
62 (96.9)
96.8%~97.0%
Febrile seizure
Yes
8 (12.5)
11.6%~13.4%
No
56 (87.5)
87.1%~87.9%
Startle response
Yes
10 (15.6)
14.6%~16.6%
No
54 (84.4)
84.0%~84.8%
Altered consciousness
Yes
1 (1.6)
1.2%~2.0%
No
63 (98.4)
98.3%~98.4%
Limb trembling
Yes
2 (3.1)
2.6%~3.6%
No
62 (96.9)
96.8%~97.0%
Unsteady gait
Yes
1 (1.6)
1.2%~2.0%
No
63 (98.4)
98.3%~98.4%
HFMD, hand-foot-and-mouth disease. Statistical analysis was performed with SPSS version 17.0 (SPSS Inc., Chicago, IL, USA). A value of was considered statistically significant.