Comparative Study of Anterior Eye Segment Measurements with Spectral Swept-Source and Time-Domain Optical Coherence Tomography in Eyes with Corneal Dystrophies

Table 1

Results of automated and manual central corneal thickness (aCCT, mCCT), anterior chamber depth (ACD), and nasal and temporal trabecular iris angle (nTIA, tTIA) measurements by swept-source optical coherence tomography SS OCT and time-domain optical coherence tomography TD OCT. Values were calculated as mean ± standard deviation (SD) or median and range depending on the sample size (<30 or ≥30). BCVA results were presented as range for all groups. EBMD = epithelial basement membrane dystrophy, TBCD = Thiel-Behnke corneal dystrophy, LCD1 = lattice corneal dystrophy TGFBI type, GCD1 = granular corneal dystrophy type 1, GCD2 = granular corneal dystrophy type 2, MCD = macular corneal dystrophy, and FECD = Fuchs endothelial corneal dystrophy.

Parameter	OCT device	Control group	Study group
CD type			EBMD	TBCD	LCD	GCD1	GCD2	MCD	FECD
Number of eyes		50 eyes	12 eyes	6 eyes	15 eyes	7 eyes	2 eyes	23 eyes	31 eyes
BCVA		1.0	1.0	0.3–0.9	0.1–0.5	0.05–0.8	0.5–0.6	0.05–0.2	0.05–0.4
aCCT; µm	TD OCT	548.96	545	600	583	550	538.5	459	675.54
		±37.34	524–586	587–615	550–620	498–567	529–548	414–492	±42.19
	SS OCT	553.96	554.5	598.5	587	546	528	453	682.03
		±31.91	518–600	578–620	546–619	480–583	518–538	419–502	±41.38
mCCT; µm	TD OCT	546.94	541.5	602	588	555	530	456	676.03
		±31.13	517–582	587–618	528–610	490–578	520–540	417–503	±43.13
	SS OCT	550.34	553.5	599.5	593	550	513	447	675.45
		±31.13	507–580	580–625	550–621	498–576	507–519	418–508	±52.98
ACD; mm	TD OCT	3.0514	3.085	2.9	3.13	3.11	3.22	3.05	2.30
		±0.24	2.71–3.45	2.71–3.15	2.71–3.59	2.72–3.24	3.06–3.39	2.61–3.59	±0.35
	SS OCT	2.9718	2.955	2.91	3.015	2.98	3.18	2.98	2.36
		±0.25	2.61–3.38	2.61–3.05	2.61–3.59	2.68–3.05	3.01–3.36	2.69–3.59	±0.46
nTIA; °	TD OCT	31.44	31	27	30	33	33	31	21.38
		±4.98	24–39	24–32	24–47	29–38	30–36	24–41	±4.40
	SS OCT	33.02	33.5	26.5	33	34	30.5	32	19.61
		±5.67	22–42	22–39	26–47	32–42	27–34	20–42	±4.49
tTIA; °	TD OCT	29.9	27.5	27	29	32	30	30	19.38
		±5.81	22–42	23–34	22–39	29–41	26–34	24–37	±5.33
	SS OCT	32.12	31.5	30	33	34	32.5	31	20.29
		±5.57	24–44	24–36	23–40	30–40	29–36	24–41	±6.01