Clinical Study

Effects of Surgical and Dietary Weight Loss Therapy for Obesity on Gut Microbiota Composition and Nutrient Absorption

Table 1

Anthropometric and clinical parameters in the dietary (VLCD) and sleeve gastrectomy (LSG) intervention group before (month 0) intervention and after 3 and 6 months.

VLCDLSG
Month 0Month 3Month 6P* trendMonth 0Month 3Month 6P* trend

Weight [kg]121.1 ± 4.9100.4 ± 4.591.3 ± 3.90.0014**127.5 ± 1.2107.0 ± 2.497.1 ± 3.0<0.0001***
BMI [kg/m2]40.2 ± 1.033.2 ± 1.030.3 ± 0.6<0.0001***45.8 ± 0.938.4 ± 1.235.0 ± 1.3<0.0001***
Waist [cm]114.7 ± 5.2104.8 ± 1.999.3 ± 1.70.0212*138.3 ± 3.6122.0 ± 4.7112.0 ± 4.20.0027**
Weight loss [kg]20.7 ± 0.429.8 ± 1.0<0.0001***20.5 ± 1.230.4 ± 1.80.0017**
RWL [%]17.2 ± 0.824.6 ± 0.80.0002***16.1 ± 1.123.9 ± 1.60.0044**

BP syst. [mmHG]120.0 ± 4.5108.3 ± 7.9108.3 ± 1.30.2352 143.3 ± 13.7110.0 ± 8.9106.7 ± 2.60.0351*
BP diast. [mmHG]83.3 ± 1.375.0 ± 3.973.3 ± 1.30.0321*85.0 ± 9.766.7 ± 2.670.0 ± 0.00.1002
Glucose [mg/dL]102.0 ± 2.196.0 ± 0.888.3 ± 2.50.0010***125.3 ± 10.494.3 ± 7.6105.0 ± 3.80.0436*
HbA1C [%]5.6 ± 0.15.3 ± 0.25.3 ± 0.00.2186 5.5 ± 0.15.3 ± 0.15.3 ± 0.20.5705
Triglycerides [mg/dL]218.0 ± 30.9113.7 ± 6.1125.7 ± 9.10.0039**169.3 ± 17.4119.0 ± 7.5117.0 ± 1.60.0086**
Cholesterol [mg/dL]224.7 ± 15.9164.0 ± 2.4176.3 ± 16.30.0165*206.0 ± 17.5188.3 ± 16.1218.7 ± 16.90.4640
HDL [mg/dL]51.3 ± 2.742.3 ± 1.854.3 ± 2.90.0147*52.0 ± 3.944.7 ± 4.248.3 ± 4.30.4827
LDL [mg/dL]143.3 ± 12.8104.3 ± 4.5108.7 ± 11.50.0383*133.0 ± 21.2 118.3 ± 21.4143.0 ± 20.80.7147

*Within group comparison.