Quercetin Increases Hepatic Homocysteine Remethylation and Transsulfuration in Rats Fed a Methionine-Enriched Diet

Figure 5

Possible targets of quercetin in homocysteine metabolic pathways in rats fed a Met-enriched diet. MS, methionine synthase; BHMT, betaine-homocysteine methyltransferase; CBS, cystathionine β-synthase; CSE, cystathionine γ-lyase; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine; Cys, cysteine; Tau, taurine; Ser, serine; Gly, glycine; GSH, reduced glutathione; THF, tetrahydrofolate; 5,10-CH₃-THF, 5,10-CH₃-tetrahydrofolate; 5-CH₃-THF, 5-CH₃-tetrahydrofolate. The arrows ( or ) indicate the changes (increase or decrease) after quercetin treatment.