Pentraxin-3 Predicts Long-Term Cardiac Events in Patients with Chronic Heart Failure

Table 4

Univariate and multivariate Cox regression analysis of major adverse cardiovascular events.

	HR	95% CI	value
Univariate analysis
Age	2.609	1.371–4.992	<0.001
Males	0.760	0.534–1.082	0.128
Heart rate	1.189	1.058–1.328	0.003
NYHA class >II	3.493	2.089–5.848	<0.001
PTX3	4.399	3.081–6.281	<0.001
cTnI	1.591	1.296–1.954	<0.001
hsCRP	1.248	1.043–1.492	0.016
CHD	0.778	0.548–1.218	0.278
Diabetes mellitus	1.013	0.978–1.048	0.477
Hypertension	0.923	0.521–1.622	0.773
Hyperlipidemia	1.022	0.989–1.055	0.193
Current smoking	1.018	0.948–1.091	0.568
Aspirin	1.091	0.793–1.501	0.594
β-blockers	0.780	0.314–1.864	0.526
ACE-I/ARB	0.962	0.710–1.385	0.962
Diuretics	0.990	0.975–1.006	0.226
Multivariate analysis
Age	2.518	1.030–6.158	0.020
PTX3	4.154	1.130–15.783	0.005
cTnI	1.808	1.208–2.686	0.008
NYHA class >II	3.018	1.818–4.998	<0.001