Review Article
Immunotherapy for Bone and Soft Tissue Sarcomas
Table 1
Cancer testis antigens in bone and soft tissue sarcomas.
| Sarcoma subtypes | Expression of cancer testis antigens | NY-ESO | LAGE | MAGE-A3 | MAGE-A4 | MAGE-A9 | PRAME | SSX-2 |
| Bone sarcomas | | | | | | | | Osteosarcoma [14] | + | + | + | + | | | | Ewing’s sarcoma [14] | + | + | + | + | | | | Chondrosarcoma [14] | + | + | + | + | | | | Soft tissue sarcomas | | | | | | | | Synovial sarcoma [15] | + | + | + | + | + | + | + | Malignant fibrous histiocytoma, pleomorphic spindle cell sarcoma [15] | + | + | + | | | + | + | Liposarcoma [15] | + | + | + | + | + | | + | Leiomyosarcoma [15] | | + | + | + | + | + | |
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