Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer’s Disease: Results of the DIAN Study

Table 1

Characteristics of the participants of the DIAN study.

Variables	Mutation carriers (MCs); ()	Noncarriers (NCs); ()	value
Age (years)	39.1 ± 10.2	39.6 ± 10.3	0.6771
Gender (M/F)	81/102	47/70	0.485
Education level (years)	13.9 ± 2.7	14.6 ± 2.7	0.0343
CDR global	0.3 ± 0.6	0.03 ± 0.1	<0.0001
CDR sum of boxes	1.64 ± 3.2	0.1 ± 0.2	<0.0001
CDR 0 (number)	107	109	0.892
CDR 0.5 (number)	48	8	<0.0001
CDR ≥ 1 (number)	28	0	n.a.
Logical memory, delayed recall (percentile)	38.5 ± 36.8	60.9 ± 31.8	<0.0001
MMSE	26.8 ± 7.5	29.03 ± 1.3	<0.0001
GDS	3.8 ± 11.2	1.3 ± 1.6	<0.0001

Mann-Whitney test; Chi-square test; CDR denotes Clinical Dementia Rating Scale; M denotes male and F denotes female; MMSE denotes Mini-Mental Status Examination; GDS denotes Geriatric Depression Scale; age, education levels, CDR sum of boxes, MMSE, logical memory, and GDS scores are displayed in mean and standard deviation.