| | Biological group | Pathway | Genes (fold change) |
| Protein metabolism and modification
() | Protein modification | Prmt3 (1.57), P4ha1 (1.53), Ptpn11 (1.66), Mapk9 (1.57), 1500003O03Rik (1.53), Man2a1 (1.71), Siat9 (1.70), St3gal5 (1.61), St6gal1 (−2.02), Trib3 (−1.93), Ppm1k (−1.56), Sgk1 (−2.53), and Plxna2 (−1.64) | | Protein folding | Hsp105 (2.75), Hspb1 (1.64), Tcp1 (1.63), Dnajb1 (1.55), Ero1lb (1.71), Hspa8 (3.15), Hspb1 (2.11), Hsp90ab1 (2.02), LOC666904 (2.22), D3Ucla1 (1.79), Hspa2 (1.69), Hsp90ab1 (1.53), Fkbp5 (1.99), Irak2 (1.55), Camk2b (1.66), Bmx (1.50), Egfr (1.75), and Clpx (−1.59) | | Proteolysis | Usp2 (3.98), Serpina12 (3.64), Serpina5 (1.61), Serpina1e (1.57), Rhbdl1 (1.56), C1s (1.52), Ahsa1 (1.68), Ppid (1.63), Bag3 (1.62), Cul4a (1.53), Serpina7 (−1.66), Serpinf2 (−1.65), Usp18 (−1.62), Itih2 (−1.61), Ulk1 (−1.54), Casp6 (−1.60), and Mug2 (−1.56) | | Protein biosynthesis | Mrps21 (1.59), Eef2 (1.58), Eif4b (1.50), and Eif4ebp3 (2.76) |
| Carbohydrate metabolism
() | Glycolysis | Gck (2.10), Pklr (1.69) | | Glycogen metabolism | Gys2 (1.92), Ppp1r3b (1.62), Pygl (1.54), and G6pc (−1.78) | | Other glycogen metabolisms | Man2a1 (1.71), Adh7 (1.67), and Tkt (2.14) | | Carbohydrate transport | Slc35b1 (1.57) | | Monosaccharide metabolism | Khk (1.68), Galt (−1.53), and Gnpda1 (−1.50) | | Other polysaccharide metabolisms | St3gal5 (1.61), Siat9 (1.70) |
| Immunity and defense
() | T-cell-mediated immunity | LOC56628 (2.05), H2-Q8 (1.72), H2-Q10 (1.52), Bmx (1.50), Raet1b (−1.63), Fkbp5 (1.99), Cxcl1 (1.60), and Gstt3 (−1.56) | | Macrophage-mediated immunity | Cish (1.92), Sdc4 (−1.65) | | Complement-mediated immunity | C6 (5.13), C9 (1.87), C8b (1.53), C1s (1.52), and Cfp (−1.51) | | Stress response | Hspa8 (3.15), Hspb1 (2.11), Hsp90ab1 (2.02), LOC666904 (2.02), D3Ucla1 (1.79), Hspa2 (1.69), Ahsa1 (1.68), and Hsp90ab1 (1.53) | | Detoxification | Gata1 (3.02), Gstp1 (2.75), Gsta3 (1.73), Gsta2 (1.59), and Gstm1 (1.55) |
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